An update on oral drug delivery via intestinal lymphatic transport

Liposomal delivery systems for intestinal lymphatic drug transport

Intestinal lymphatic drug delivery has been widely studied because drugs can bypass the first-pass metabolism in the liver via the lymphatic route, which increases oral bioavailability. Various lipid-based nanoparticles have been used to deliver hydrophobic drugs to the lymphatic pathway. This review focuses on the liposomal delivery systems used for intestinal lymphatic drug transport. Liposom...

Oral drug delivery utilizing intestinal OATP transporters.

Transporters play important roles in tissue distribution and urinary- and biliary-excretion of drugs and transporter molecules involved in those processes have been elucidated well. Furthermore, an involvement of efflux transporters such as P-glycoproteins, multidrug resistance associated protein 2, and breast cancer resistance protein as the intestinal absorption barrier and/or intestinal lumi...

A review on electrospun nanofibers for oral drug delivery

Nowadays, polymer nanofibers have gained attention due to remarkable characteristics such as high porosity and large surface area to volume ratio. Among their fabrication methods, electrospinning technique has been attracted as a simple and reproducible approach. It is a versatile, simple and cost-effective technique for the production of continuous nanofibers with acceptable characteristics su...

Strategies of Mucoadhesive Drug Delivery System- an Update on Nasal Drug Delivery

and Sanjay Garg * T An Update on Osmotic Drug Delivery

www.pharmtech.com herapeutically active molecules for the treatment and prevention of new and existing diseases are currently being developed. Although pharmacological activity is the primary requirement for a molecule to be used as a therapeutic agent, it is equally important that the molecule reach its site of action—hence the role of drug delivery technologies. Scientists are pursuing the di...